Mapping the 'social network' of proteins in the cell to understand how genes shape living things

One of biology's fundamental questions is how our genes shape who we are. Adrian Serohijos and Stephen Michnick, professors in the Department of Biochemistry and Molecular Medicine at Université de Montréal's Faculty of Medicine, are studying the relationship between genotype and phenotype, that is, how DNA becomes RNA, then protein, and ultimately gives rise to observable characteristics in an individual or any other living organism. "We're trying to unravel the mechanisms of the genome, specifically how the information it encodes is processed inside the cell," Serohijos says.